TG 100-115, CAS 677297-51-7

Shelf life (days): 730

Info: A PI3Kγ and PI3Kδ inhibitor (IC50s = 0.083 and 0.235 µM, respectively); selective for PI3Kγ and PI3Kδ over PI3Kα and PI3Kβ (IC50s = 1.3 and 1.2 µM); inhibits TRPM7 kinase activity (IC50 = 1.07 µM); inhibits the migration and invasion of MDA-MB-231 breast cancer cells at 50 µM; prevents VEGF- or histamine-induced intradermal edema and PAF- or dextran-induced hind paw edema and leukocyte infiltration in rats at 1 and 5 mg/kg, respectively; decreases infarct size as a percentage of the area at risk in a porcine model of myocardial infarction induced by coronary artery occlusion at 0.5 mg/kg

Formulation: A crystalline solid

Formal Name: 3,3’-(2,4-diamino-6,7-pteridinediyl)bis-phenol

Purity: ≥95%

Formula Markup: C18H14N6O2

Formula Weight: 346.3

CAS Number: 677297-51-7

• Artikelnummer: CAY10010512-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10010512-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK