THK-5117, CAS 1374107-54-6

Product Description: THK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a Ki of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD)  brain homogenates. 18F-THK-5117 has the potential to act as a tau imaging PET probe[1].

Applications: Neuroscience-Neurodegeneration

Formula: C19H19FN2O2

References: [1]Nobuyuki Okamura, et al. Novel 18F-labeled arylquinoline derivatives for noninvasive imaging of tau pathology in Alzheimer disease. J Nucl Med. 2013 Aug;54(8):1420-7.

CAS Number: 1374107-54-6

Molecular Weight: 326.36

Compound Purity: 98.52

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Microtubule/Tubulin

• Artikelnummer: MEXHY-101182-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-101182-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK