Clone Name: 7D3
Application Note: WB: 1:100 - 1:1000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 24
Specificity/Sensitivity: This antibody recognizes human TIMP-3 in western blot. No cross-reactivity to human TIMP-1, 2 and 4 is noted.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008]
Uniprot ID: P35625
Antigen Species: Human
Immunogen: Human recombinant TIMP-3 protein
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: TIMP metallopeptidase inhibitor 3
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