Clone: R111
Specificity: Human TNFRSF1A. No cross-reactivity with Mouse TNFR1 in ELISA
Antibody Modification: Preservative Free Unconjugated
Presentation: 0.2 µm filtered histidine and arginine buffer containing 120mM NaCl, 0.02% Tween 80, pH 6.0
Immunogen: Recombinant Human TNFR1 / CD120a / TNFRSF1A protein
Gene: TNFRSF1A / TNFR1
Description: TNFR1 antibody LS-C819187 is an unconjugated rabbit monoclonal antibody to human TNFR1 (TNFRSF1A). Validated for Block, ELISA and Neut.
Usage: Block: In a functional ELISA which immobilized recombinant Human TNFR1 at 0.2 ug/ml (100 µL/well) in the plate, the Rabbit anti-Human Monoclonal Antibody can block the binding of 0.5 ug/ml of biotinylated Human TNFa to human TNFR1, the EC50 is 4. 66 ug/ml. Neutralization: The neutralization activity of TNFR1/TNFRSF1A Neutralizing Antibody is Measured by its ability to neutralize TNFR1/TNFRSF1A-mediated inhibition of cytotoxicity in the L-929 mouse fibroblast cell line. The Neutralization titer (IC50) is typically 0.5-1. 5 µg/mL in the presence of 0.3 ug/ml Recombinant Human TNFR1/TNFRSF1A, 0.2 ng/mL Recombinant Human TNFa and 1 µg/mL actinomycin D. Please Note: Optimal concentrations/dilutions should be determined by the end user.
Synonyms: TNFRSF1A, CD120a, CD120a antigen, MS5, p60, TBP1, TNF-R55, TNFAR, TNFR1, p55-R, TNF-R, TNF-R-I, TNF-R1, TNF-RI, Tnfr, TNFR-I, TNFR1-d2, TNFR60, FPF, p55, Tbpi, TNFR55
Recommended Storage: Store at 2°C to 8°C for up to 1 month. Aliquot and store at -20°C to -80°C for up to 1 year. Avoid freeze/thaw cycles.
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