Application Note: WB: 0.1-1μg/ml. IHC-P: 5-10μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 56
Positive Control: The peptide used to generate this antibody is available for purchase (GTX89650-PEP).
Specificity/Sensitivity: This antibody is expected to recognise both reported isoforms.
Form: Liquid
Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain; domains which typically participate in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. This protein has been shown to interact with Tollip, clathrin and ubiquitin and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 that is associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Apr 2017]
Uniprot ID: Q6ZVM7
Antigen Species: Human
Immunogen: Peptide with sequence CRKKPERSEDALFAL, from the C Terminus of the protein sequence according to NP_001028723.1; NP_001076437.1.
Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation: Unconjugated
Full Name: target of myb1 like 2 membrane trafficking protein