Formal Name: uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid, tetrasodium salt
Purity: ≥95%
Formula Markup: C9H11N2O14P3S / 4Na
Formula Weight: 588.135083
Notes: Uridine-5'-O-(3-thiotriphosphate) (UTP-γ-S) is a hydrolysis-resistant derivative of UTP (Item No. 9003530) an agonist of the purinergic P2Y2 receptor.{72039} It induces inositol phosphate formation in 1321N1 astrocytoma cells expressing the human P2Y2 receptor (EC50 = 240 nM) and chloride secretion in primary nasal epithelial cells from patients with cystic fibrosis in a concentration-dependent manner. UTP-γ-S induces vasoconstriction in isolated human coronary arteries (EC50 = 25.1 µM).{72040}