Product Description: Viloxazine (Viloxazin) is a norepinephrine reuptake inhibitor, also a potent 5-HT2C agonist and 5-HT2B antagonist with an EC50 of 32 μM and an IC50 of 27 μM for 5-HT2C and 5-HT2B, respectively. The mechanism of action of Viloxazine predominantly involves serotonergic and noradrenergic pathways. Viloxazine can be used for researching depression[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C13H19NO3
References: [1]Yu C, et al. New Insights into the Mechanism of Action of Viloxazine: Serotonin and Norepinephrine Modulating Properties. J Exp Pharmacol. 2020 Aug 25;12:285-300./[2]Pinder RM, et al. Viloxazine: a review of its pharmacological properties and therapeutic efficacy in depressive illness. Drugs. 1977 Jun;13(6):401-21.
CAS Number: 46817-91-8
Molecular Weight: 237.29
Compound Purity: 99.15
Research Area: Neurological Disease
Solubility: DMSO : ≥ 120 mg/mL
Target: 5-HT Receptor;Adrenergic Receptor