Clone Name: ACGI-19
Application Note: WB: 1:500-1:2000. ICC/IF: 1:50-1:150. IP: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 55
Form: Liquid
Buffer (with preservative): PBS, 150mM NaCl, 0.04-0.05% BSA, 50% Glycerol, 0.02% Sodium Azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
Uniprot ID: Q9UPY5
Antigen Species: Human
Immunogen: A synthesized peptide derived from human xCT.
Conjugation: Unconjugated
Full Name: solute carrier family 7 member 11
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