YM-58483, CAS 223499-30-7

CRAC channel  blocker

Product Type: Blocker.

CAS No.: 223499-30-7.

MolecularFormula: C15H9F6N5OS.

Molecular Weight: 421,3.

Source: Synthetic.

Purity: >98% (TLC); NMR (Conforms).

Solubility: May be dissolved in DMSO (40 mg/ml).

Appearance: Off-white powder.

PubChem CID: 2455.

Scientific Background: YM-58483 is a calcium release-activated calcium channel blocker. It inhibits antigen-induced histamine release via modulation of mast cell responses. It also is a potent T-cell antiproliferative agent.

References: 1. Zitt. C., et al. (2004) J. Biol. Chem. 279(13): 12427-12437. 2. Law M., et al. (2001) Int. J. Biochem. Cell Biol. 43:1228-1239. 3. K Ohga et al. (2008) Int. Immunopharmacol. 8:1787-1792.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-606-25MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-606-25MG
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK