Product Description: 1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) is a chelating agent. 1,2-Cyclohexylenedinitrilotetraacetic acid has an ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate[1].
Applications: Metabolism-sugar/lipid metabolism
Formula: C14H22N2O8
References: [1]Tandon SK, et al. Removal of manganese by chelating agents from brain and liver of manganese treated rats: as in vitro and an in vivo study. Toxicology. 1975 Nov;5(2):237-41./[2]Sun Y, et al., Synthesis and characterization of racemic mixture and meso isomers of bis(trans-2-aminocyclohexyl)aminepentaacetic acid and the stabilities of their Gd(III) complexes. Inorg Chem. 2000 Apr 3;39(7):1480-6./[3]Hazell AS, et al., Alzheimer type II astrocytic changes following sub-acute exposure to manganese and its prevention by antioxidant treatment. Neurosci Lett. 2006 Apr 3;396(3):167-71.
CAS Number: 482-54-2
Molecular Weight: 346.33
Compound Purity: 98.0
Research Area: Neurological Disease
Solubility: DMSO : 5.83 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Biochemical Assay Reagents
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