1-Azakenpaullone, CAS 676596-65-9

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 9-bromo-7,12-dihydro-pyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one

Purity: ≥98%

Formula Markup: C15H10BrN3O

Formula Weight: 328.2

CAS Number: 676596-65-9

Notes: 1-Azakenpaullone is an analog of kenpaullone (Item No. 10010239) that inhibits glycogen synthase kinase 3β (GSK3β) more potently (IC50 = 18 nM) than CDK1/cyclin B or CDK5/p25 (IC50s = 2.0 and 4.2 µM, respectively).{27328} Through its effects on GSK3β, 1-azakenpaullone stimulates the proliferation of human pancreatic islets and drives the differentiation of mouse embryonic stem cells and Nematostella larvae.{27329,27331,27330}

• Artikelnummer: CAY16733-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16733-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK