1-Deoxygalactonojirimycin (hydrochloride), CAS 75172-81-5

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: (2R,3S,4R,5S)-2-(hydroxymethyl)-3,4,5-piperidinetriol, monohydrochloride

Purity: ≥98%

Formula Markup: C6H13NO4 / HCl

Formula Weight: 199.6

CAS Number: 75172-81-5

Notes: 1-Deoxygalactonojirimycin is a competititve inhibitor of α-galactosidase (IC50 = 40 nM).{28089} At subinhibitory concentrations, 1-Deoxygalactonojirimycin binds to α-galactosidase and chaperones unstable enzyme variants through the endoplasmic reticulum, allowing its movement into lysosomes.{28088,28086} Pharmacological chaperones, including 1-Deoxygalactonojirimycin, are used to promote lysosomal delivery of unstable proteins in lysosomal storage disorders, like Fabry disease.{28086}

• Artikelnummer: CAY17179-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 17179-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK