Product Description: 1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) sodium, a potent bioactive phospholipid, is a LPA receptor activator. 1-Oleoyl lysophosphatidic acid sodium can promote mitosis by inducing DNA synthesis. 1-Oleoyl lysophosphatidic acid sodium is also involved in normal and pathological emotional responses, including anxiety and depression[1][2][3].
Applications: Neuroscience-Neuromodulation
Formula: C21H40NaO7P
References: [3]Castilla-Ortega E, et, al. 1-Oleoyl lysophosphatidic acid: a new mediator of emotional behavior in rats. PLoS One. 2014 Jan 7;9(1):e85348./[1]Corven EJ, et, al. Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suramin. Biochem J. 1992 Jan 1;281 ( Pt 1)(Pt 1):163-9./[2]Lapierre DM, et, al. Lysophosphatidic acid signals through multiple receptors in osteoclasts to elevate cytosolic calcium concentration, evoke retraction, and promote cell survival. J Biol Chem. 2010 Aug 13;285(33):25792-801.
CAS Number: 325465-93-8
Molecular Weight: 458.50
Compound Purity: 99.29
Research Area: Neurological Disease
Solubility: DMSO : 1.85 mg/mL (ultrasonic;warming;adjust pH to 5 with HCl;heat to 60°C)/H2O : 25 mg/mL (ultrasonic)
Target: LPL Receptor
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