116-9e, CAS 831217-43-7

Product Description: 116-9e (MAL2-11B) is a Hsp70 co-chaperone DNAJA1 inhibitor. 116-9e inhibits Simian Virus 40 (SV40) replication and DNA synthesis. 116-9e inhibits tumor antigen (TAg)’s endogenous ATPase activity and the TAg-mediated activation of Hsp70[1][2].

Applications: COVID-19-anti-virus

Formula: C31H32N2O5

References: [1]Christine M Wright, et al. Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen. Virus Res. 2009 Apr;141(1):71-80./[2]Nitika, et al. Chemogenomic screening identifies the Hsp70 co-chaperone DNAJA1 as a hub for anticancer drug resistance. Sci Rep. 2020 Aug 14;10(1):13831.

CAS Number: 831217-43-7

Molecular Weight: 512.60

Compound Purity: 98.55

Research Area: Cancer; Infection

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: DNA/RNA Synthesis;HSP

• Artikelnummer: MEXHY-116683-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-116683-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK