13,14-dihydro-15-keto Prostaglandin D2-d4

Shelf life (days): 730.0

Formulation: A solution in methyl acetate

Formal Name: 9a-hydroxy-11,15-dioxo-prost-5Z-en-1-oic-3,3,4,4-d4 acid

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C20H28D4O5

Formula Weight: 356.5

Notes: 13,14-dihydro-15-keto Prostaglandin D2-d4 (13,14-dihydro-15-keto PGD2-d4) is intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGD2 (Item No. 12610) by GC- or LC-mass spectrometry. 13,14-dihydro-15-keto PGD2 is a metabolite of PGD2 which is formed through the 15-hydroxy PGDH pathway. 13,14-dihydro-15-keto PGD2 was recently identified as a selective agonist for the CRTH2/DP2 receptor.{5248} It also inhibits ion flux in a canine colonic mucosa preparation.{9769} In humans, 13,14-dihydro-15-keto PGD2 is further metabolized to give 11β-hydroxy compounds which have also undergone β-oxidation of one or both side chains. Virtually no 13,14-dihydro-15-keto PGD2 survives intact in the urine.{418,35}

• Artikelnummer: CAY10007978-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10007978-50
• Verpackungseinheit: 50 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung