Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (1R,4R)-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one
Purity: ≥98%
Formula Markup: C10H16O
Formula Weight: 152.2
CAS Number: 464-49-3
Notes: (1R)-(+)-Camphor is a terpene that has been found in C. sativa, C. indica, and C. sativa/C. indica hybrid strains as well as the essential oils from a variety of herbs including rosemary, lavender, and sage and has diverse biological activities.{42303,42305,42306,42307,42308,42304} It inhibits norepinephrine secretion and cytosolic calcium and sodium increases induced by the nicotinic acetylcholine receptor (nAChR) agonist 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP) in chromaffin cells (IC50s = 70, 88, and 19 μM, respectively).{42305} (1R)-(+)-Camphor (65-260 μM) induces proliferation of and increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in human primary dermal fibroblasts.{42306} In vivo, (1R)-(+)-camphor increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in skin in UV-exposed mice when administered at doses of 26 and 55 mM in drinking water post UV-exposure. It reduces cough frequency in citric acid-challenged guinea pigs.{42307} (1R)-(+)-Camphor is insecticidal, reducing digging activity and inducing mortality of fire ant workers.{42308} It has also been used as a building block in the synthesis of cannabinergic ligands.{42304}
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