Product Description: (1S,2S,3R)-DT-061 is an enantiomer of DT-061 (HY-112929). DT-061 is an orally active activator of protein phosphatase 2A (PP2A). (1S,2S,3R)-DT-061 can be used as a negative control in the research of KRAS-mutant and MYC-driven lung cancer tumorigenesis[1].
Applications: Cancer-programmed cell death
Formula: C25H23F3N2O5S
References: [1]Kauko O, et al. PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells. Sci Transl Med. 2018 Jul 18;10(450). pii: eaaq1093.
CAS Number: 1809427-20-0
Molecular Weight: 520.52
Compound Purity: 99.77
Research Area: Cancer
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: Phosphatase