2,3-DCPE (hydrochloride), CAS 1009555-55-8

2,3-DCPE (hydrochloride), CAS 1009555-55-8
Artikelnummer
CAY10005229-50
Verpackungseinheit
50 mg
Hersteller
Cayman Chemical

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Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2-[[3-(2,3-dichlorophenoxy)propyl]amino]-ethanol, monohydrochloride

Purity: ≥98%

Formula Markup: C11H15Cl2NO2 / HCl

Formula Weight: 300.6

CAS Number: 1009555-55-8

Notes: 2,3-DCPE is a proapoptotic compound with selectivity for cancer cells versus normal human cells. It induces apoptosis in vitro in various cancer cell lines (IC50s = 0.89-2.69 µM) more effectively than in normal human fibroblasts (IC50 = 12.6 µM). 2,3-DCPE down-regulates Bcl-xL, however forced overexpression of Bcl-xL is sufficient to block 2,3-DCPE apoptosis induction.{11853} 2,3-DCPE can induce S-phase arrest, upregulate p21, and activate ERK.{14281}
Mehr Informationen
Artikelnummer CAY10005229-50
Hersteller Cayman Chemical
Hersteller Artikelnummer 10005229-50
Verpackungseinheit 50 mg
Mengeneinheit STK
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