Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 2-[[3-(2,3-dichlorophenoxy)propyl]amino]-ethanol, monohydrochloride
Purity: ≥98%
Formula Markup: C11H15Cl2NO2 / HCl
Formula Weight: 300.6
CAS Number: 1009555-55-8
Notes: 2,3-DCPE is a proapoptotic compound with selectivity for cancer cells versus normal human cells. It induces apoptosis in vitro in various cancer cell lines (IC50s = 0.89-2.69 µM) more effectively than in normal human fibroblasts (IC50 = 12.6 µM). 2,3-DCPE down-regulates Bcl-xL, however forced overexpression of Bcl-xL is sufficient to block 2,3-DCPE apoptosis induction.{11853} 2,3-DCPE can induce S-phase arrest, upregulate p21, and activate ERK.{14281}