2'-Deoxyuridine 5'-monophosphate, CAS 964-26-1

Product Description: 2'-Deoxyuridine 5'-monophosphate (dUMP) is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C9H13N2O8P

References: [1]Zachary Newby, et al. The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261. Biochemistry. 2006 Jun 20;45(24):7415-28./[2]Skouloubris S, et al. Targeting of Helicobacter pylori thymidylate synthase ThyX by non-mitotoxic hydroxy-naphthoquinones. Open Biol. 2015 Jun;5(6):150015.

CAS Number: 964-26-1

Molecular Weight: 308.18

Research Area: Infection; Metabolic Disease

Target: Endogenous Metabolite

• Artikelnummer: MEXHY-W394006-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W394006-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK