Product Description: 2-MNG (2-Mercaptonicotinoyl glycine) is an inhibitor for melanogenesis with an average IC50 of 49.5μM in normal human melanocytes. 2-MNG binds to melanin precursors, prevents the incorporation into growing melanin, and thereby inhibits the synthesis of eumelanin and pheomelanin. 2-MNG can be used in research about skin pigmentation[1].
Formula: C8H8N2O3S
References: [1]Sextius P, et al., 2-Mercaptonicotinoyl glycine, a new potent melanogenesis inhibitor, exhibits a unique mode of action while preserving melanocyte integrity. Pigment Cell Melanoma Res. 2024 Jul;37(4):462-479.
CAS Number: 2101538-28-5
Molecular Weight: 212.23
Compound Purity: 98.04
Research Area: Others
Solubility: DMSO : 116.67 mg/mL (ultrasonic)
Target: Others