3-Acetyl-7-Hydroxycoumarin, CAS 10441-27-7

Product Description: 3-Acetyl-7-Hydroxycoumarin (Compound 2) is a high selective 17-beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitor. 3-Acetyl-7-Hydroxycoumarin shows a significant improvement of the inhibitory potency, with 57% inhibition of 17β-HSD1 at 6 μM. 3-Acetyl-7-Hydroxycoumarin is promising for research of hormone-dependent diseases, such as breast cancer and endometriosis[1].

Formula: C11H8O4

References: [1]Starcević S, et al. Synthesis and biological evaluation of (6- and 7-phenyl) coumarin derivatives as selective nonsteroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1. J Med Chem. 2011 Jan 13;54(1):248-61.

CAS Number: 10441-27-7

Molecular Weight: 204.18

Research Area: Cancer; Endocrinology

Target: 17β-HSD

• Artikelnummer: MEXHY-W267205-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W267205-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK