Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 3-bromo-L-tyrosine, monotrifluoroacetate salt
Purity: ≥95%
Formula Markup: C9H10BrNO3 / CF3COOH
Formula Weight: 374.1
CAS Number: 2320428-62-2
Notes: 3-Bromotyrosine is a product of protein oxidation found after activation of eosinophils during an allergic response.{39006,39007,39009} It has been used as a marker of eosinophil peroxidase-induced protein oxidation in vitro and in vivo.{39007,39010} In addition to its production in eosinophils, 3-bromotyrosine is found at 5-fold higher levels in peritoneal exudate from mice infected with K. pneumoniae compared with uninfected animals, suggesting neutrophils release higher levels of oxidized products during inflammation.{39011} In a human study, 3-bromotyrosine was increased 10-fold in allergen-challenged lung samples from subjects with allergen-induced asthma.{39007}
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