4-Bromo-3-hydroxybenzoic acid, CAS 14348-38-0

Product Description: 4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of 1 mM for both rat fetal and rat gastric HDC. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC50s of 1 mM for both enzymes[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C7H5BrO3

References: [1]Ellenbogen L, et al. Studies on the inhibition of histidine decarboxylase, aromatic-L-amino acid decarboxylase and acid secretion by brocresine and its metabolites. Biochem Pharmacol. 1973 Apr 15;22(8):939-47./[2]Qian S, et al. Inhibiting Histamine Signaling Ameliorates Vertigo Induced by Sleep Deprivation. J Mol Neurosci. 2019 Mar;67(3):411-417.

CAS Number: 14348-38-0

Molecular Weight: 217.018

Compound Purity: 99.25

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Endogenous Metabolite

• Artikelnummer: MEXHY-W003445-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W003445-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK