5-hydroxy Diclofenac, CAS 69002-84-2

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-[(2,6-dichlorophenyl)amino]-5-hydroxy-benzeneacetic acid

Purity: ≥95%

Formula Markup: C14H11Cl2NO3

Formula Weight: 312.2

CAS Number: 69002-84-2

Notes: 5-hydroxy Diclofenac is an active metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor diclofenac (Item Nos. 70680 / 22983).{14145,64745} It is formed by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C9, CYP2C19, and CYP1A2.{64744} 5-hydroxy Diclofenac is cytotoxic to HL-60 leukemia cells (IC50 = 661 µM).{61708} It induces apoptosis and increases caspase-3 activity in rat hepatocytes in a concentration-dependent manner.{64745}

• Artikelnummer: CAY23369-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23369-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK