Shelf life (days): 1825.0
Formulation: A neat solid
Formal Name: (5α,6β)-17-(cyclopropylmethyl)-4,5-epoxy-morphinan-3,6,14-triol
Purity: ≥98%
Formula Markup: C20H25NO4
Formula Weight: 343.4
CAS Number: 49625-89-0
Notes: 6β-Naltrexol (Item No. 15896) is an analytical reference material that is structurally categorized as an opioid. It is the major metabolite of naltrexone (Item Nos. ISO60192 / 15520).{32375} Unlike naltrexone, which acts as a µ-receptor antagonist or inverse agonist, 6β-naltrexol is a neutral opioid antagonist.{32377} 6β-Naltrexol binds the µ-opioid receptor more potently than naloxone (Item Nos. ISO60191 / 15594) or naltrexone (Kis = 94, 420, and 265 pM, respectively) but is ~100-fold less effective at blocking morphine-modulated pain in vivo, as assessed using the mouse hotplate test.{32376} This product is intended for research and forensic applications.
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