Product Description: 8-Hydroxyguanosine, an oxidized nucleoside, is a marker of RNA oxidative damage and oxidative stress. 8-Hydroxyguanosine stimulates proliferation and differentiation of B cells[1][2][3].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C10H13N5O6
References: [1]Fiala ES, et al. Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane. Cancer Res. 1989 Oct 15;49(20):5518-22./[2]Abe T, et al. Remarkable increase in the concentration of 8-hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer's disease. J Neurosci Res. 2002 Nov 1;70(3):447-50./[3]Ahmad A, et al. 8-Hydroxyguanosine and 8-methoxyguanosine possess immunostimulating activity for B lymphocytes. Cell Immunol. 1985 Aug;94(1):276-80.
CAS Number: 3868-31-3
Molecular Weight: 299.24
Compound Purity: 99.91
Research Area: Metabolic Disease; Neurological Disease
Solubility: DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Endogenous Metabolite
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