Shelf life (days): 730.0
Formulation: A solution in methyl acetate
Formal Name: (±)9(10)epoxy-12Z-octadecenoic 9,10,12,13-d4 acid
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C18H28D4O3
Formula Weight: 300.5
Notes: (±)9,10-EpOME-d4 is intended for use as an internal standard for the quantification of (±)9(10)-EpOME (Item No. 52400) by GC- or LC-MS. (±)9(10)-EpOME is the 9,10-cis epoxide of linoleic acid (Item No. 90150), generated by neutrophils during the oxidative burst.{651} It has been recovered from the lungs of hyperoxic rats and from humans with acute respiratory distress syndrome.{407} Mitochondrial dysfunction is the main feature of (±)9(10)-EpOME cytotoxicity, which may be due to the diol metabolites as well as the parent epoxide.{1300,5617}