A23187, CAS 52665-69-7

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 5-(methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl-4-benzoxazolecarboxylic acid

Purity: ≥98%

Formula Markup: C29H37N3O6

Formula Weight: 523.6

CAS Number: 52665-69-7

Notes: A23187 is a calcium ionophore and a microbial metabolite that has been found in S. chartreusensis.{20152,35484} It induces calcium overload and mitochondrial apoptosis in HEK293 cells when used at a concentration of 5 µM.{20152} A23187 (5 µM) induces the production of reactive oxygen species (ROS) and neutrophil extracellular trap (NET) formation in primary human neutrophils in a myeloperoxidase-, neutrophil elastase-, and citrullination-independent manner.{35484}

• Artikelnummer: CAY11016-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 11016-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK