Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl-methanone
Purity: ≥98%
Formula Markup: C7H10N4O
Formula Weight: 166.18066
CAS Number: 1312782-34-5
Notes: AA26-8 is a pan-serine hydrolase inhibitor.{66178} It inhibits acylaminoacyl-peptide hydrolase (APEH), platelet-activating factor acetylhydrolase 2 (PAF-AH2), α/β hydrolase domain-containing protein 11 (ABHD11), lysophospholipase 1 (LYPLA1), fatty acid amide hydrolase (FAAH), and neutral cholesterol ester hydrolase 1 (NCEH1) when used at a concentration of 1 µM. AA26-8 (10 µM) also inhibits the interaction of the α/β hydrolase Dwarf14 (D14) and a negative regulator of its signaling, D53, induced by the plant growth regulator GR24 (Item No. 13210) in a yeast two-hybrid assay.{66179}