Product Description: AA26-9 is a potent and broad spectrum serine hydrolase inhibitor. AA26-9 targets included serine peptidases, lipases, amidases, esterases, and thioesterases. AA26-9 shows inhibitory activity against approximately 1/3 of the 40+ serine hydrolases detected in immortalized T cell lines [1][2].
Applications: Metabolism-sugar/lipid metabolism
Formula: C7H10N4O
References: [1]Adibekian A, et al. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nat Chem Biol. 2011 May 15;7(7):469-78./[2]Borne AL, et al. Deciphering T Cell Immunometabolism with Activity-Based Protein Profiling. Curr Top Microbiol Immunol. 2019;420:175-210.
CAS Number: 1312782-34-5
Molecular Weight: 166.18
Compound Purity: 99.42
Research Area: Metabolic Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : ≥ 100 mg/mL
Target: Phospholipase