Description of Target: High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain (By similarity). May play a role in early stem cell self-renewal by blocking differentiation.
Immunogen: Recombinant ABCG2 (Leu63~Leu349) expressed in E.coli
Molecular Weight: 73 kDa
Product Format: Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Protein Name: ATP-binding cassette sub-family G member 2
Purification: Affinity Purified; Protein A Purified
Specificity#: The antibody is a rabbit polyclonal antibody raised against ABCG2. It has been selected for its ability to recognize ABCG2 in immunohistochemical staining and western blotting.
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