AC 187, CAS 151804-77-2

Product Description: AC 187 is a potent and orally active amylin receptor antagonist with an IC50 of 0.48 nM and a Ki of 0.275 nM. AC 187 shows more selective for amylin receptor than calcitonin and CGRP receptors. AC 187 has neuroprotective effects[1][2].

Formula: C127H205N37O40

References: [1]Jack H Jhamandas, et al. Antagonist of the amylin receptor blocks beta-amyloid toxicity in rat cholinergic basal forebrain neurons. J Neurosci. 2004 Jun 16;24(24):5579-84./[2]Bronislava R Gedulin, et al. Role of endogenous amylin in glucagon secretion and gastric emptying in rats demonstrated with the selective antagonist, AC187. Regul Pept. 2006 Dec 10;137(3):121-7.

CAS Number: 151804-77-2

Molecular Weight: 2890.25

Compound Purity: 98.86

Research Area: Endocrinology

Solubility: 10 mM in DMSO

Target: Amylin Receptor

• Artikelnummer: MEXHY-P1393-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P1393-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK