Product Description: ACY-957 is an orally active and selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9[1].
Formula: C24H23N5OS
References: [1]Shearstone JR, et al. Chemical Inhibition of Histone Deacetylases 1 and 2 Induces Fetal Hemoglobin through Activation of GATA2. PLoS One. 2016 Apr 13;11(4):e0153767.
CAS Number: 1609389-52-7
Molecular Weight: 429.54
Compound Purity: 99.66
Research Area: Others
Solubility: DMSO : 83.33 mg/mL (ultrasonic)
Target: HDAC