Clone Name: H341
Light Chain: Kappa
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Positive Control: Brain: A moderate to strong adenosine A1 receptor staining should be seen in the molecular layer of cerebellum.
Negative Control: Kidney: Most epithelial and endothelial cells must be negative.
Specificity/Sensitivity: <b>Highly recommended for IHC-P in human tissues.</b>
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 1 mg/ml
Background: The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot ID: P30542
Antigen Species: Human
Immunogen: Synthetic peptide encompassing a sequence within the Intracellular domain of human Adenosine A1 Receptor. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: adenosine A1 receptor
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