AdipoRon, CAS 924416-43-3

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2-(4-benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]-acetamide

Purity: ≥98%

Formula Markup: C27H28N2O3

Formula Weight: 428.5

CAS Number: 924416-43-3

Notes: Adiponectin expressed by adipocytes exerts antidiabetic effects by binding to adiponectin receptor (AdipoR)1, which activates AMPK pathways, and AdipoR2, which activates PPARα pathways. AdipoRon is an orally active small molecule AdipoR agonist that binds AdipoR1 and AdipoR2 with KD values of 1.8 and 3.1 µM, respectively.{25721} At 50 mg/kg, it acts similarly to adiponectin, activating AMPK and PPARα pathways and reducing insulin resistance and glucose intolerance in wild type mice fed a high-fat diet and in genetically obese db/db mice.{25721}

• Artikelnummer: CAY15941-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 15941-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK