Fas Ligand, Mouse (P.pastoris, His)

Don’t miss this promotion: enjoy a 20% discount on all recombinant proteins for our supplier MedChem Express until December 31, 2025. These special prices are already discounted – no additional discounts can be applied during the promotion period.

Product Description: Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development[1]. Mouse Fas Ligand has a total length of 279 amino acids (M1-L279), with a TNF_2 domain (144-279 a.a.). Fas Ligand Protein, Mouse (P.pastoris, His) is a recombinant protein expressed in P.pastoris cells with N-terminal His-tag.

Formula: 14103(Gene_ID)Q544E9 (P132-L279)(Accession)

References: [1]Schneider P, et al. Characterization of Fas (Apo-1, CD95)-Fas ligand interaction. J Biol Chem. 1997 Jul 25;272(30):18827-33./[2]Liu W, et al. Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3. Structure. 2016 Nov 1;24(11):2016-2023./[3]Martínez-Lorenzo MJ, et al. Release of preformed Fas ligand in soluble form is the major factor for activation-induced death of Jurkat T cells. Immunology. 1996 Dec;89(4):511-7./[4]Puppo F, et al. Fas, Fas ligand, and transfusion immunomodulation. Transfusion. 2001 Mar;41(3):416-8./[5]Miwa K, et al. Caspase 1-independent IL-1beta release and inflammation induced by the apoptosis inducer Fas ligand. Nat Med. 1998 Nov;4(11):1287-92./[6]Shudo K, et al. The membrane-bound but not the soluble form of human Fas ligand is responsible for its inflammatory activity. Eur J Immunol. 2001 Aug;31(8):2504-11.

Molecular Weight: Approximately 18.2 kDa

Compound Purity: 94.40

• Artikelnummer: MEXHY-P74157-50UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P74157-50UG
• Verpackungseinheit: 50 μg
• Mengeneinheit: STK