IL-1 beta, Rhesus macaque

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Product Description: IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions[1][2].  IL-1 beta Protein, Rhesus macaque consists of 153 amino acids (A117-S269) and is expressed in E. coli.

Formula: 704701(Gene_ID)P48090 (A117-S269)(Accession)

References: [1]Jan Petrasek, et al. IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice. J Clin Invest. 2012 Oct;122(10):3476-89./[2]Karina Zitta, et al. Interleukin-1beta regulates cell proliferation and activity of extracellular matrix remodelling enzymes in cultured primary pig heart cells. Biochem Biophys Res Commun. 2010 Sep 3;399(4):542-7./[3]Kenichi Shimada, et al. Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection. PLoS One. 2011;6(6):e21477.

Molecular Weight: Approximately 18.4 kDa

Compound Purity: 98.0

• Artikelnummer: MEXHY-P7207-20UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P7207-20UG
• Verpackungseinheit: 20 μg
• Mengeneinheit: STK