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Recombinant Mouse Ccl24 Protein(Trx Tag)

Recombinant Mouse Ccl24 Protein(Trx Tag)
Artikelnummer
ELSPDEM100130-1
Verpackungseinheit
1 mg
Hersteller
Elabscience Biotechnology

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Protein Tag: N-Trx

Uniprot: Q9JKC0

Accession: Q9JKC0

Background: CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. CCL24 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 is chemotactic for resting T-lymphocytes, and eosinophils. It has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Eotaxin-2 interacts with an chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated level of Eotaxin-2 has been seen in patients with an aspirin-exacerbated respiratory disease.

Bio Acitivity: Not validated for activity

Sequence: Val27-Val119

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.

Calculated MW: 30.1 kDa

Observed MW: 33 kDa
Mehr Informationen
Artikelnummer ELSPDEM100130-1
Hersteller Elabscience Biotechnology
Hersteller Artikelnummer PDEM100130-1
Verpackungseinheit 1 mg
Mengeneinheit STK
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