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Protein Tag: N-Trx
Uniprot: Q9JHH5
Accession: Q9JHH5
Background: I-TAC, also known as CXCL1/Lymphotactin1/I-TAC, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL1/Lymphotactin0. I-TAC is chemotactic for activated T cells. The CXCL1/Lymphotactin1/I-TAC gene is located on human chromosome 4 along with many other members of the CXC chemokine family.
Bio Acitivity: Not validated for activity
Sequence: Phe22-Met100
Purity: > 90% as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.
Calculated MW: 28.5 kDa
Observed MW: 31 kDa
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