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Protein Tag: N-Trx
Uniprot: O54824
Accession: O54824
Background: Interleukin 16, also known as lymphocyte chemoattractant factor (LCF), refers to the C-terminal peptide of Mouse pro-IL-16 or neuronal IL-16, which are nuclear and cytoplasmic PD2 domain containing proteins. The C-termini of these proteins are cleaved by Caspase-3, resulting in the release of secreted IL-16. Mature IL-16 has been shown to bind the cell surface receptor CD4 and function as an immunomodulatory cytokine. The C-terminal peptide of human and Mouse IL-16 share approximately 86% amino acid sequence identity.
Bio Acitivity: Not validated for activity
Sequence: Ser1205-Ser1322
Purity: > 90% as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.
Calculated MW: 33 kDa
Observed MW: 33 kDa
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