Recombinant Mouse NT-proBNP Protein(Trx Tag)

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Protein Tag: N-Trx

Uniprot: P40753

Accession: P40753

Background: Brain-type Natriuretic Peptide (BNP) is a nonglycosylated peptide that is produced predominantly by ventricular myocytes and belongs to the natriuretic peptide family. Proteolytic cleavage of the 12 kDa BNP precursor gives rise to N-terminal Pro BNP (NT-proBNP) and mature BNP. N-terminal proB-type natriuretic peptide (NT-proBNP), a useful marker of heart failure (HF), is considered to be secreted mainly from the ventricle, increased serum NT-proBNP levels are also encountered in conditions such as atrial fibrillation (AF) and atrial septal defect in patients without HF.

Bio Acitivity: Not validated for activity

Sequence: Ser26-Arg76

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin: < 10 EU/mg of the protein as determined by the LAL method

Calculated MW: 25.5 kDa

Observed MW: 30 kDa

• Artikelnummer: ELSPDEM100111-500
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: PDEM100111-500
• Verpackungseinheit: 500μg
• Mengeneinheit: STK