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Protein Tag: C-Fc
Uniprot: P09326
Accession: P09326
Background: Cluster of Differentiation 48 (CD48) , also known as SLAMF2 , BCM-1 and BLAST-1 , is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion , pathogen recognition , cellular activation , and cytokine regulation , and emerges as a critical effector molecule in immune responses.
Bio Acitivity: Not validated for activity
Sequence: Gln27-Ser220
Purity: > 90% as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.
Calculated MW: 46.2 kDa
Observed MW: 60 kDa
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