Recombinant Human DKK-3 Protein(His Tag)

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Protein Tag: C-His

Uniprot: Q9UBP4

Accession: Q9UBP4

Background: DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1 , DKK2 , DKK3 and DKK4. It is a secreted protein , and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.

Bio Acitivity: Not validated for activity

Sequence: Ala22-Ile350

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 36.0 kDa

Observed MW: 50 kDa

• Artikelnummer: ELSPDMH100318-1
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: PDMH100318-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK