Recombinant Human EGF Protein(Fc Tag)

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Protein Tag: C-Fc

Uniprot: P01133

Accession: P01133

Background: This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants

Bio Acitivity: Not validated for activity

Sequence: Asn971-Arg1023

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 30.7 kDa

Observed MW: 30-40 kDa

• Artikelnummer: ELSPDMH100210-1
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: PDMH100210-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK