Recombinant Human IL2RA Protein(Fc Tag)

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Protein Tag: C-Fc

Uniprot: P01589

Accession: P01589

Background: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with an the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with an interleukin 2 receptor alpha deficiency.

Bio Acitivity: Not validated for activity

Sequence: Glu22-Gln240

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 48.9 kDa

Observed MW: 60 kDa

• Artikelnummer: ELSPDMH100268-1
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: PDMH100268-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK