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Protein Tag: C-Fc
Uniprot: O54901
Accession: O54901
Background: Predicted to enable protein binding activity involved in heterotypic cell-cell adhesion. Involved in negative regulation of cell population proliferation, negative regulation of macrophage activation, and negative regulation of neuroinflammatory response. Located in cell surface. Is expressed in several structures, including anterior naris, aorta, bone, nervous system, and retina. Used to study autoimmune disease. Orthologous to human CD200 (CD200 molecule).
Bio Acitivity: Not validated for activity
Sequence: Gln31-Gly232
Purity: > 90% as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.
Calculated MW: 47.1 kDa
Observed MW: 60 kDa
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