Recombinant Rat CXCL5/LIX Protein(Sumo Tag)

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Protein Tag: N-Sumo

Uniprot: P97885

Accession: P97885

Background: CXCL5 is a small cytokine belonging to the CXC chemokine family. CXC chemokines are particularly significant for leukocyte infiltration in inflammatory diseases. CXCL5 is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. It also can be detected in eosinophils, and can be inhibited with the type II interferon. CXCL5 plays a role in reducing sensitivity to sunburn pain in some subjects, and is a potential target which can be utilized to understand more about pain in other inflammatory conditions like arthritis and cystitis. It stimulates the chemotaxis of neutrophils possesses angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2.

Bio Acitivity: Not validated for activity

Sequence: Ala38-Lys117

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.

Calculated MW: 21.7 kDa

Observed MW: 29 kDa

• Artikelnummer: ELSPDER100134-500
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: PDER100134-500
• Verpackungseinheit: 500μg
• Mengeneinheit: STK