ALD1613

Product Description: ALD1613 is a potent neutralizing monoclonal antibody against adrenocorticotropic hormone (ACTH). ALD1613 neutralizes ACTH-induced signaling and inhibits ACTH-induced cyclic AMP accumulation in a mouse adrenal cell line (Y1) via all five melanocortin receptors. ALD1613 significantly reduces plasma corticosterone levels in wild-type rats. ALD1613 can be used in the study of diseases associated with elevated ACTH levels[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: N/A

References: [1]Andrew L Feldhaus, et al. ALD1613, a Novel Long-Acting Monoclonal Antibody to Control ACTH-Driven Pharmacology. Endocrinology. 2017 Jan 1;158(1):1-8.

Molecular Weight: N/A

Research Area: Metabolic Disease

Target: Melanocortin Receptor

• Artikelnummer: MEXHY-P991221-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P991221-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK
• Konjugat: Unconjugated