Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (8a,9ß,11ß,14ß,23S,24R)-24,25-epoxy-11,23-dihydroxy-dammar-13(17)-en-3-one
Purity: ≥98%
Formula Markup: C30H48O4
Formula Weight: 472.69972
CAS Number: 18649-93-9
Notes: Alisol B is a triterpene that has been found in A. orientale and has diverse biological activities.{63254,63255,63256} It increases the number of LC3 puncta, a marker of autophagy, as well as induces cell cycle arrest at the G1 phase and apoptosis, in MCF-7 breast cancer cells when used at a concentration of 30 µM.{63254} Alisol B (0.5-5 µM) inhibits RANKL-induced osteoclast differentiation of mouse bone marrow-derived macrophages (BMDMs).{63255} It reduces increases in ear thickness in a mouse model of delayed-type hypersensitivity induced by picryl chloride when administered at doses of 10 or 50 mg/kg.{63256}
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