Aloxistatin (Standard), CAS 88321-09-9

Aloxistatin (Standard), CAS 88321-09-9
Artikelnummer
MEXHY-100229R-0
Verpackungseinheit
Get quote
Hersteller
MedChemExpress

Verfügbarkeit: wird geladen...
Preis wird geladen...
Product Description: Aloxistatin (Standard) is the analytical standard of Aloxistatin. This product is intended for research and analytical applications. Aloxistatin (E64d) is a cell-permeable and irreversible broad-spectrum cysteine protease inhibitor. Aloxistatin (E64d) exhibits entry-blocking effect for MERS-CoV.

Formula: C17H30N2O5

References: [1]Doh-Ura K, et al. Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation. J Virol. 2000 May;74(10):4894-7./[2]Konjar S, et al. Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L. Immunology. 2010 Oct;131(2):257-67./[3]Mullins SR, et al. Three-dimensional cultures modeling premalignant progression of human breast epithelial cells: role of cysteine cathepsins. Biol Chem. 2012 Dec;393(12):1405-16./[4]Hook G, et al. The cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activity. J Alzheimers Dis. 2011;26(2):387-408./[5]Cheng XW, et al. Superoxide-dependent cathepsin activation is associated with hypertensive myocardial remodeling and represents a target for angiotensin II type 1 receptor blocker treatment. Am J Pathol. 2008 Aug;173(2):358-69./[6]Ji Yeun Kim, et al. Safe, High-Throughput Screening of Natural Compounds of MERS-CoV Entry Inhibitors Using a Pseudovirus Expressing MERS-CoV Spike Protein. Int J Antimicrob Agents. 2018 Nov;52(5):730-732.

CAS Number: 88321-09-9

Molecular Weight: 342.43

Research Area: Neurological Disease

Target: Cathepsin;Reference Standards;SARS-CoV
Mehr Informationen
Artikelnummer MEXHY-100229R-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-100229R-0
Verpackungseinheit Get quote
Mengeneinheit STK
Produktinformation (PDF)
×
MSDS (PDF)
×